Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mutation-driven mechanisms underlying antibiotic resistance of Helicobacter pylori in Asia: A systematic review and meta-analysis (2000-2024).

Microbial pathogenesis·2026
Same author

An Unusual Case of Juvenile Dermatomyositis Complicated by Macrophage Activation Syndrome.

International journal of dermatology·2026
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Basic Science and Pathogenesis.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Neuroprotective Potential of Free Radical-Scavenging Nanoparticles in Addressing Inflammation and Obesity.

IET nanobiotechnology·2025
Same author

Results of a 2025 UK and Ireland survey on the use of minimal phototoxic dose testing before psoralen with ultraviolet A radiation phototherapy.

Clinical and experimental dermatology·2025
Same journal

Drug-Induced Subacute Cutaneous Lupus Erythematosus Associated with Fenofibrate Lipid Lowering Agent.

Skinmed·2025
Same journal

Racial Disparities in the Management of Atopic Dermatitis: An Analysis of the National Ambulatory Medical Care Survey, 2012-2018.

Skinmed·2025
Same journal

"Pseudo-Chik Sign" Following COVID-19: Pigmentation Hitherto Unreported.

Skinmed·2025
Same journal

Hyperpigmented Scaly Lesions in the Axillae.

Skinmed·2025
Same journal

Sweet Syndrome-Like Disorder Induced by the Oxford-AstraZeneca<sup>®</sup> SARS-CoV-2 Vaccine.

Skinmed·2025
Same journal

Lockdown Lessons from Dermatology Consultations during the COVID-19 Pandemic in a Tertiary Care Center.

Skinmed·2025
See all related articles

Related Experiment Video

Updated: May 16, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Footwear dermatitis: pathogenesis--part I.

Virendra N Sehgal1, Farhan Rasool, Govind Srivastava

  • 1Dermato-Venereology (Skin/VD) Center, Sehgal Nursing Home, Panchwati, Delhi, India. drsehgal@ndf.vsnl.net.in

Skinmed
|November 21, 2012
PubMed
Summary
This summary is machine-generated.

Footwear dermatitis, a common skin condition, is caused by various changing materials in shoes. Identifying these triggers is key to managing this dermatological issue effectively.

Related Experiment Videos

Last Updated: May 16, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Area of Science:

  • Dermatology
  • Materials Science

Background:

  • Footwear dermatitis is a significant dermatological concern.
  • The causes of footwear dermatitis are evolving due to changes in the footwear industry.

Purpose of the Study:

  • To highlight the diverse and changing etiological factors in footwear dermatitis.
  • To underscore the importance of identifying specific triggers in footwear materials.

Main Methods:

  • Review of current literature on footwear dermatitis.
  • Analysis of common and emerging causative agents in shoe construction.

Main Results:

  • Identified a wide spectrum of allergens and irritants in footwear.
  • Highlighted materials such as leather, rubber accelerators, dyes, and metal trims as common culprits.
  • Noted the dynamic nature of these causative factors.

Conclusions:

  • Continuous vigilance and updated knowledge are essential for diagnosing and managing footwear dermatitis.
  • Understanding the evolving composition of footwear is crucial for dermatologists and patients alike.