Related Experiment Videos
Septic arthritis due to Staphylococcus warneri: a diagnostic challenge
Barbara Legius1, Kristel Van Landuyt, Patrick Verschueren
1Division of Rheumatology, University Hospital KU Leuven, Belgium.
The Open Rheumatology Journal
|November 21, 2012
Summary
Diagnosing indolent septic arthritis from Staphylococcus Warneri can be difficult. Arthroscopic tissue cultures may aid in identifying this skin commensal infection, even in immunocompetent patients.
Area of Science:
- Infectious Diseases
- Rheumatology
- Microbiology
Background:
- Septic arthritis presents diagnostic challenges, particularly indolent infections.
- Staphylococcus Warneri is an emerging cause of septic arthritis, often linked to prosthetic devices.
Observation:
- A case of a 38-year-old immunocompetent male with Staphylococcus Warneri septic arthritis following intensive care unit stay is presented.
- This infection was caused by a commensal skin bacterium, highlighting non-prosthetic device related cases.
Findings:
- Indolent Staphylococcus Warneri infections can mimic other conditions, delaying diagnosis.
- Arthroscopic tissue cultures are crucial for accurate identification of the causative pathogen.
Implications:
- Early and accurate diagnosis of Staphylococcus Warneri septic arthritis is essential for effective treatment.
- Increased awareness of this pathogen is needed, especially in post-ICU patients.
- Arthroscopy plays a key role in the diagnostic pathway for challenging septic arthritis cases.
Related Concept Videos
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:29Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
01:26Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
01:25Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...