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The impact of percutaneous coronary intervention on ischemic mitral regurgitation

Anna M Booher1, Stanley J Chetcuti, David S Bach

  • 1Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA. amanion@med.umich.edu

The Journal of Heart Valve Disease
|November 22, 2012
PubMed

Insights

Significant ischemic mitral regurgitation (IMR) is common in patients undergoing multi-vessel percutaneous coronary intervention (PCI) but is not improved by the procedure. Inadequate pre-PCI echocardiography may lead to missed diagnoses of IMR.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Imaging

Background:

  • Ischemic mitral regurgitation (IMR) is a concern in patients undergoing multi-vessel percutaneous coronary intervention (PCI).
  • The effectiveness of PCI in addressing significant IMR requires further investigation.

Purpose of the Study:

  • To determine if significant ischemic mitral regurgitation (IMR) is adequately addressed in patients undergoing multi-vessel percutaneous coronary intervention (PCI).

Main Methods:

  • A retrospective analysis of a cardiac catheterization laboratory database over five years.
  • Inclusion of patients who underwent multi-vessel PCI.
  • Assessment of pre- and post-revascularization echocardiographic data, clinical data, and outcomes.

Main Results:

  • Out of 150 patients undergoing PCI, 96 had complete pre- and post-procedural echocardiograms.
  • 22% of patients had moderate or greater IMR.
  • The severity of IMR did not significantly change after multi-vessel PCI.

Conclusions:

  • Clinically significant IMR is not uncommon in patients treated with multi-vessel PCI.
  • Percutaneous revascularization did not significantly alter IMR severity.
  • Inadequate pre-PCI echocardiography in over one-third of patients suggests potential underdiagnosis of IMR.
Abstract

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