Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems related to...
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The consequences of <i>Shigella</i> medically-attended diarrhoea and other leading pathogens among young children living in high-burden settings: a multi-country prospective cohort study.

EClinicalMedicine·2026
Same author

Artificially Sweetened and Sugar-Sweetened Beverage Intake and Risk of Liver Cancer.

JAMA network open·2026
Same author

Cessation of Betel Quid Chewing, Smoking, and Alcohol Drinking and Risk of Oral Precancer and Oral Cancer.

JCO global oncology·2026
Same author

Sex differences in cancer incidence persist across race and ethnicity.

Biology of sex differences·2026
Same author

Real-World Effectiveness of Rotavirus Vaccine Against Rotavirus Disease Among Children < 2 Year of Age in Mali.

Journal of the Pediatric Infectious Diseases Society·2026
Same author

Sociodemographic characteristics of populations living near industrial land disposals of known and suspected carcinogens across the United States.

Journal of exposure science & environmental epidemiology·2026
Same journal

Reconsidering ambiguous language in infectious disease consult recommendations.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Antibiotic Treatment Duration for Uncomplicated Monomicrobial Enterococcal Bloodstream Infection: A Multicenter Target Trial Emulation.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Larger Blood Volume Increases Detection of Fastidious Mycobacteria and Fungi in Blood Culture.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Anticalcitonin: Limited utility of a context-dependent biomarker demonstrated in another real-world data set.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Procalcitonin Testing in Community-Acquired Pneumonia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Wanted: A Relevant Correlate of Protection for Dengue Vaccines.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
See all related articles

Related Experiment Video

Updated: May 16, 2026

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

Statistical methods in the Global Enteric Multicenter Study (GEMS).

William C Blackwelder1, Kousick Biswas, Yukun Wu

  • 1Center for Vaccine Development, University of Maryland School of Medicine, 685 W Baltimore St, Baltimore, MD 21201, USA. wblackwe@medicine.umaryland.edu

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|November 22, 2012
PubMed
Summary
This summary is machine-generated.

The Global Enteric Multicenter Study (GEMS) quantified moderate-to-severe diarrhea (MSD) in young children across Africa and Asia. This research identified key pathogens contributing to childhood diarrhea, informing public health interventions.

Related Experiment Videos

Last Updated: May 16, 2026

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

Area of Science:

  • Global Health
  • Pediatric Infectious Diseases
  • Epidemiology

Background:

  • Diarrheal diseases remain a leading cause of mortality and morbidity in children under five years globally.
  • Accurate data on the burden and causative agents of moderate-to-severe diarrhea (MSD) are crucial for effective public health strategies in resource-limited settings.

Purpose of the Study:

  • To investigate the burden, incidence, and attributable causes of moderate-to-severe diarrhea (MSD) in children under 60 months of age.
  • To estimate the population attributable fraction for specific pathogens causing MSD in sub-Saharan Africa and South Asia.

Main Methods:

  • The Global Enteric Multicenter Study (GEMS) enrolled children under 60 months with MSD at sentinel health centers across seven sites.
  • Conditional logistic regression was used to estimate the odds ratio of MSD associated with pathogen isolation.
  • Population attributable fractions were calculated using isolation proportions, odds ratios, and site-specific population data.

Main Results:

  • GEMS provided comprehensive data on the incidence and burden of MSD in the study regions.
  • Specific enteric pathogens were identified as significant contributors to MSD, with varying attributable fractions.
  • Associations between MSD, specific pathogens, and outcomes like death and malnutrition were evaluated.

Conclusions:

  • The study established the significant burden of MSD in young children in sub-Saharan Africa and South Asia.
  • Identifying key causative pathogens allows for targeted interventions and resource allocation to reduce childhood diarrhea.
  • Findings from GEMS inform global efforts to control diarrheal diseases and improve child survival.