Related Experiment Video
Updated: May 16, 2026
Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
Published on: March 14, 2025
Experimental periodontitis and peri-implantitis in dogs
Olivier Carcuac1, Ingemar Abrahamsson, Jean-Pierre Albouy
1Department of Periodontology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Aim:
To analyze the tissue reactions following ligature removal in experimental periodontitis and peri-implantitis in dogs.
Material And Methods:
Four implants with similar geometry and with two different surface characteristics (turned/TiUnite Nobel BioCare AB, Göteborg) were placed pair-wise in a randomized order in the right side of the mandible 3 months after tooth extraction in 5 dogs. Experimental peri-implantitis and periodontitis were initiated 3 months later by ligature placement around implants and mandibular premolars and plaque formation. The ligatures were removed after 10 weeks, and block biopsies were obtained and prepared for histological analysis 6 months later.
Results:
It was demonstrated that the amount of bone loss that occurred during the period following ligature removal was significantly larger at implants with a modified surface than at implants with a turned surface and at teeth. The histological analysis revealed that peri-implantitis sites exhibited inflammatory cell infiltrates that were larger, extended closer to the bone crest and contained larger proportions of neutrophil granulocytes and osteoclasts than in periodontitis.
Conclusion:
It is suggested that lesions produced in experimental periodontitis, and peri-implantitis are different and that implant surface characteristics influence the inflammatory process in experimental peri-implantitis and the magnitude of the resulting tissue destruction.
