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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

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FDG PET and PET/CT.

Berud J Krause1, Sarah Schwarzenböck, Michael Souvatzoglou

  • 1Department of Nuclear Medicine, Universitätsklinikum Rostock, Rostock, Germany. bernd.krause@med.uni-rostock.de

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|November 27, 2012
PubMed
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Positron emission tomography/computed tomography (PET/CT) with (18)F-fluorodeoxyglucose (FDG) is a valuable tool in oncology. FDG PET/CT aids in diagnosing, staging, and monitoring various cancers, including lung, breast, and colorectal, and can predict prognosis.

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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Area of Science:

  • Oncology
  • Nuclear Medicine
  • Medical Imaging

Background:

  • Molecular imaging with positron emission tomography (PET) is widely used in oncology.
  • Hybrid PET/CT imaging combines molecular and morphologic information for comprehensive patient assessment.
  • The glucose analogue (18)F-fluorodeoxyglucose (FDG) is the most common radiopharmaceutical for PET and PET/CT in clinical oncology.

Purpose of the Study:

  • To discuss the clinical applications and indications of FDG PET and PET/CT in oncology.
  • To review current literature on FDG PET/CT for primary diagnosis, staging, and recurrence detection in various cancers.
  • To explore the role of FDG PET/CT in assessing therapy response, influencing treatment planning, and predicting prognosis.

Main Methods:

  • Review of current literature on FDG PET and PET/CT in oncology.
  • Focus on specific cancer types: lung, oesophageal, colorectal, head and neck, lymphoma, and breast cancer.
  • Analysis of FDG PET/CT's utility in primary diagnosis, staging, re-staging, and detection of recurrent disease (local, lymph node, distant metastases).

Main Results:

  • FDG PET/CT is an efficient tool for whole-body staging and re-staging in oncologic patients.
  • The modality is crucial for primary diagnosis, staging, and detecting recurrent disease across multiple cancer types.
  • Emerging evidence supports FDG PET/CT's role in therapy response assessment and prognosis prediction.

Conclusions:

  • FDG PET/CT is integral to the diagnosis, staging, and monitoring of cancer patients.
  • Its application extends to evaluating treatment effectiveness and predicting patient outcomes.
  • FDG PET/CT significantly impacts therapeutic management and treatment planning in oncology.