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Serum calcium level in hypertension

Mohammed Abdul Hannan Hazari1, Mehnaaz Sameera Arifuddin, Syed Muzzakar

  • 1Department of Physiology, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad, Andhra Pradesh, India.

North American Journal of Medical Sciences
|November 28, 2012
PubMed

Insights

Serum calcium levels are tightly regulated and do not significantly correlate with blood pressure in individuals with or without hypertension. This suggests subtle calcium level variations do not impact blood pressure regulation.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nephrology

Background:

  • Extracellular calcium levels may influence intracellular calcium and play a role in essential hypertension pathogenesis.
  • Understanding calcium's role in hypertension is crucial for developing effective treatments.

Purpose of the Study:

  • To investigate the association between serum calcium levels and hypertension.
  • To compare serum calcium levels in normotensive individuals, hypertensive patients on calcium channel blockers, and those on other antihypertensive medications.

Main Methods:

  • Study included 31 participants: 12 normotensive and 19 hypertensive individuals.
  • Hypertensive participants were categorized based on medication: calcium channel blockers or other antihypertensives.
  • Serum calcium levels were measured using the Accucare Calcium Arsenazo III kit, with statistical analysis via ANOVA.

Main Results:

  • No significant difference in serum calcium levels was observed between normotensive and hypertensive groups.
  • No correlation was found between serum calcium levels and blood pressure.
  • Serum calcium levels did not significantly differ between hypertensive patients on calcium channel blockers versus those on other antihypertensive drugs.

Conclusions:

  • Serum calcium levels are subject to tight physiological regulation.
  • Minor fluctuations in serum calcium levels do not appear to affect blood pressure in the studied population.
Abstract

Keywords:
Antihypertensive medicationCalcium channel blockerHypertensionNormotensionSerum calcium

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