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Updated: May 16, 2026
04:22
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
[Persistent genital arousal disorder: a systematic review]
Summary
Persistent genital arousal disorder (PGAD) affects 1% of the population and is linked to overactive bladder and restless legs syndrome. Management requires a multidisciplinary approach for effective treatment.
Area of Science:
- Gynecology
- Urology
- Neurology
Background:
- Persistent genital arousal disorder (PGAD) is a newly recognized condition.
- Proper recognition of PGAD is crucial to avoid misdiagnosis and inappropriate labeling of affected individuals.
Purpose of the Study:
- To provide guidance on the recognition and management of Persistent Genital Arousal Disorder (PGAD).
- To highlight the importance of avoiding psychological misinterpretations of PGAD symptoms.
Main Methods:
- A comprehensive literature review was conducted using major databases (PubMed, Medline, Embase, Cochrane).
- Search terms included "persistent genital arousal", "restless genital syndrome", "persistent genital arousal syndrome", and "persistent sexual arousal syndrome".
- 37 articles out of 300 reviewed were found to be relevant to PGAD.
Main Results:
- PGAD prevalence is estimated at 1%, potentially more common than previously suspected.
- Associated conditions include overactive bladder (OAB), restless legs syndrome (RLS), and pelvic varices.
- Genital sensations are described as unwanted and intrusive, often occurring at the clitoris, labia, or vagina.
Conclusions:
- This review offers guidance for clinicians in managing patients with PGAD.
- A multidisciplinary approach involving history, examination, and investigations like pelvic MRI is recommended.
- Treatment options include psychological therapies, psychotropic medications (e.g., clonazepam), and transcutaneous electrical nerve stimulation (TENS).
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