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Updated: Feb 12, 2026

Fabricating Highly Open Porous Microspheres HOPMs via Microfluidic Technology
Published on: May 16, 2022
A novel microfluidic approach for monodispersed chitosan microspheres with controllable structures
Jian-Hong Xu1, Hong Zhao, Wen-Jie Lan
1The State Key Lab of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, 100084, Beijing, PR China. xujianhong@tsinghua.edu.cn
Abstract:
A novel and simple approach to prepare monodispersed chitosan microspheres with relative small size and controlled structures was developed by combining the solidification methods of solvent extraction and chemical crosslinking in a capillary-embedded microfluidic decive. The microspheres with different structures are used in the field of protein drug controlled release and immobilization lipases and they show different release profiles and good stability, respectively.
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