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Updated: May 16, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
Published on: April 29, 2007
Failure to consider a radically new scientific idea or theory
1Massachusetts College of Pharmacy & Health Sciences, Boston, Massachusetts 02115, USA. michael.montagne@mcphs.edu
Abstract:
From plate tectonics theory to psychoneuroimmunology, to medical uses of marijuana, and controlled drinking by alcoholics, there has been a consistent failure by scientists and medical researchers to consider radically new ideas and theories. A review and analysis of these cases and other examples identified numerous reasons or barriers for this failure. Learning from these episodes of failure requires attention to and reflection on these barriers, an understanding of how the scientific process progresses and scientific knowledge evolves, and a willingness to test and evaluate these new ideas and theories before passing final judgment on them.
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