Related Experiment Video
Updated: May 16, 2026
Using Retinal Imaging to Study Dementia
Published on: November 6, 2017
Quantification of retinal nerve fiber layer thickness using spectral domain optical coherence tomography in normal
Tarannum Mansoori1, Kalluri Viswanath, Nagalla Balakrishna
1Vasan Eye Care, Secunderabad, Andhra Pradesh, India.
Abstract:
The purpose of this study was to measure peripapillary retinal nerve fiber layer thickness (RNFLT) using spectral domain optical coherence tomography (SD-OCT) in normal Indian eyes, for which, 210 normal volunteers were recruited. One eye of each subject underwent RNFL scanning at 3.4 mm circle diameter around optic nerve using SD OCT. The data were analyzed to determine RNFLT in the sample population and its variation with age and gender. The average peripapillary RNFLT was 114.03 ± 9.59 μm. There was no effect of gender on RNFLT parameters. Age had significant negative correlation with average (P = 0.005), superior (P = 0.04), temporal (P = 0.049), and nasal quadrants (P = 0.01) RNFLT. Inferior quadrant RNFLT also had a negative correlation with age, but it was not statistically significant (P = 0.15).
