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Published on: May 19, 2020
Infective endocarditis presenting as an isolated aneurysm of the posterior mitral leaflet
Philippe Unger1, Martine Antoine, Delfyne Hastir
1Department of Cardiology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium. philippe.unger@erasme.ulb.ac.be
Abstract:
We describe the case of a 64-year-old woman in whom an aneurysm located on the posterior mitral leaflet was detected. Blood cultures grew methicillin-sensitive Staphylococcus epidermidis, and histologic examination of the operative specimen showed polymorphonuclear neutrophilic infiltration of the valve wall associated with fibrin and necrosis, consistent with a diagnosis of endocarditis. The posterior mitral location of the aneurysm and the absence of vegetation are exceptionally rare in this setting. This case demonstrates that a mitral aneurysm may be the sole cardiac presentation of infective endocarditis.
Insights
A rare case of infective endocarditis presented solely as a mitral valve aneurysm. This finding highlights the importance of considering endocarditis in unusual cardiac presentations.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathology
Background:
- Infective endocarditis typically presents with vegetations on heart valves.
- Mitral valve aneurysms are uncommon cardiac findings.
Observation:
- A 64-year-old woman presented with an aneurysm on the posterior mitral leaflet.
- Blood cultures identified methicillin-sensitive Staphylococcus epidermidis.
- Histology revealed valve wall inflammation, fibrin, and necrosis.
Findings:
- The mitral aneurysm, without vegetations, was the primary manifestation of endocarditis.
- The posterior mitral leaflet location is an exceptionally rare site for this condition.
Implications:
- This case underscores that infective endocarditis can manifest solely as a mitral valve aneurysm.
- Clinicians should consider endocarditis in the differential diagnosis of isolated mitral aneurysms.
- Further research may elucidate the pathogenesis of endocarditis-associated mitral aneurysms.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Regurgitation I: Introduction
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Regurgitation II: Clinical Features and Diagnostic Tests

