Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Heck's disease.

P J Lamey1, M A Lewis, J S Rennie

  • 1Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School.

British Dental Journal
|March 24, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Examining Premeditation and Urgency as Moderators of the Longitudinal Association Between Alcohol-Induced Blackouts and AUDIT Scores Among Adolescents and Young Adults.

Substance use & misuse·2025
Same author

Host Diversification May Split Epidemic Spread into Two Successive Fronts Advancing at Different Speeds.

Bulletin of mathematical biology·2022
Same author

A hybrid gravity and route choice model to assess vector traffic in large-scale road networks.

Royal Society open science·2020
Same author

HEREDITARY ENDOCRINE TUMOURS: CURRENT STATE-OF-THE-ART AND RESEARCH OPPORTUNITIES: MEN1-related pancreatic NETs: identification of unmet clinical needs and future directives.

Endocrine-related cancer·2020
Same author

A method for screening groundwater vulnerability from subsurface hydrocarbon extraction practices.

Journal of environmental management·2019
Same author

Global patterns of nitrate storage in the vadose zone.

Nature communications·2017

Focal epithelial hyperplasia (Heck's disease) is a rare oral condition. This study describes clinical and histological findings in two Caucasian adults, reviewing existing literature on this uncommon disease.

Area of Science:

  • Oral Pathology
  • Dermatology
  • Infectious Diseases

Background:

  • Focal epithelial hyperplasia (FEH), also known as Heck's disease, is a benign epithelial hyperplasia of the oral mucosa.
  • It is considered a viral-induced condition, often associated with human papillomavirus (HPV).
  • FEH is most common in children and indigenous populations, making adult Caucasian cases rare.

Observation:

  • This report details the clinical presentation and histological examination of two adult Caucasian patients diagnosed with focal epithelial hyperplasia.
  • The lesions were observed in the oral cavity, consistent with typical FEH locations.
  • Diagnostic procedures included biopsy and microscopic analysis to confirm the histological features.

Findings:

  • Histological examination revealed characteristic features of epithelial hyperplasia, acanthosis, and parakeratosis.

Related Experiment Videos

  • Clinical findings in both patients were consistent with the typical presentation of focal epithelial hyperplasia.
  • The cases highlight the occurrence of FEH in adult Caucasians, a demographic less commonly affected.

    • Implications:

    • The findings contribute to the understanding of focal epithelial hyperplasia's clinical spectrum and demographic variations.
    • This review emphasizes the importance of considering FEH in the differential diagnosis of oral lesions, even in atypical patient groups.
    • Further research may elucidate the specific viral or host factors influencing FEH development in diverse populations.