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Published on: February 6, 2019
[Evolution of prostate cancer brachytherapy]
Jean-Michel Hannoun-Levi1, Daniel Chevallier, Jean-Marc Cosset
1Département de radiothérapie, Université Nice-Sophia, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice Cedex, France. jean-michel.hannoun-levi@nice.unicancer.fr
Bulletin Du Cancer
|December 12, 2012
Summary
Brachytherapy, an established prostate cancer treatment, has advanced with technology. This review covers its evolution, techniques like low- and high-dose rate brachytherapy, and future research directions.
Area of Science:
- Oncology
- Radiotherapy
- Medical Physics
Context:
- Brachytherapy, or curietherapy, is a long-standing radiotherapy technique for prostate cancer.
- Technological and scientific advancements have significantly influenced its development and application.
- Understanding its historical evolution is crucial for appreciating current and future applications.
Purpose:
- To provide a historical overview of prostate brachytherapy's evolution.
- To discuss current technical aspects, including low-dose rate (LDR) and high-dose rate (HDR) brachytherapy, and advanced imaging.
- To outline evidence-based indications for various prostate cancer risk groups and explore potential future research.
Summary:
- This review details the historical progression of prostate brachytherapy, from its origins to modern techniques.
- It examines LDR brachytherapy (permanent/temporary implants), HDR brachytherapy, and contemporary imaging modalities.
- Indications are presented based on evidence-based medicine for low, intermediate, and high-risk prostate cancers, alongside emerging research areas like focal therapy and single-dose HDR brachytherapy.
Impact:
- Provides a comprehensive resource on prostate brachytherapy for clinicians and researchers.
- Highlights the integration of technological progress in cancer treatment evolution.
- Informs clinical practice and guides future research in prostate cancer radiotherapy.

