[Clinical features and follow-up study of neonatal asymmetric crying facies]

Cheng-Qiu Lu1, Xiao-Lei Zhuang, Chen Chu

  • 1Gynecology and Obstetrics Hospital, Fudan University, Shanghai, China.

Insights

Neonatal asymmetric crying facies (ACF) often co-occurs with other congenital malformations. While short-term outcomes for infants with ACF are generally good, long-term monitoring is essential for optimal prognosis.

Area of Science:

  • Neonatology
  • Pediatric Neurology
  • Clinical Genetics

Context:

  • Asymmetric crying facies (ACF) is a congenital condition affecting facial muscle development.
  • Early recognition and understanding of associated conditions are crucial for infant care.

Purpose:

  • To evaluate the clinical characteristics of neonatal asymmetric crying facies (ACF).
  • To assess the short-term outcomes of infants diagnosed with ACF.
  • To improve the diagnostic recognition of ACF.

Summary:

  • A retrospective study of 11 infants with ACF identified associations with other congenital malformations, including ear malformations, congenital heart disease, and limb anomalies.
  • Maternal and paternal age, parity, and history of diabetes mellitus were noted.
  • Neurological assessments at corrected gestational ages of 44 weeks and 3 months showed generally satisfactory development, despite persistent ACF.

Impact:

  • ACF is frequently linked to other congenital anomalies, highlighting the need for comprehensive screening.
  • Short-term outcomes for infants with ACF appear favorable.
  • Long-term follow-up and interdisciplinary collaboration are recommended to optimize the prognosis for affected infants.
Abstract

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