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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
[Multiple sclerosis in Argentina. Systematic review and meta-analysis]
Juan Ignacio Rojas1, Liliana Patrucco, Edgardo Cristiano
1Servicio de Neurología, Clínica de Esclerosis Múltiple, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. juan.rojas@hospitalitaliano.org.ar
Medicina
|December 18, 2012
Summary
This systematic review and meta-analysis reveals the epidemiological profile of multiple sclerosis (MS) in Argentina. Key findings include a prevalence of 17 cases per 100,000 and an incidence of 1.76 cases per 100,000 persons-years.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Multiple sclerosis (MS) is a chronic neurological disease with a variable epidemiological distribution worldwide.
- Understanding the specific epidemiological characteristics of MS in Argentina is crucial for public health planning and resource allocation.
Purpose of the Study:
- To conduct a systematic review and meta-analysis to establish the epidemiological profile of multiple sclerosis in Argentina.
- To consolidate existing data on MS prevalence, incidence, and clinical subtypes within the Argentine population.
Main Methods:
- A systematic search of electronic databases and reference lists was conducted to identify relevant epidemiological studies on MS in Argentina.
- Data from 15 selected studies were analyzed using StatsDirect software to synthesize prevalence, incidence, and demographic information.
- Prevalence was reported in four studies, with a mean of 17 cases per 100,000 inhabitants.
Main Results:
- The estimated prevalence of MS in Argentina is approximately 17 cases per 100,000 inhabitants.
- The incidence, based on one hospital-based study, was found to be 1.76 cases per 100,000 person-years.
- The most common MS subtype was relapsing-remitting MS (65.5%), followed by secondary progressive MS (21.5%). The female-to-male ratio was 1.55:1.
Conclusions:
- This meta-analysis provides a comprehensive overview of the current epidemiological landscape of multiple sclerosis in Argentina.
- The findings highlight the need for continued research to expand the understanding of MS in the country and inform targeted interventions.
