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Updated: May 15, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
Published on: July 28, 2023
[Keloids on dark skin: a consecutive series of 456 cases]
G H Yedomon1, H Adegbidi, F Atadokpede
1Service de dermatologie-IST, Centre national hospitalier universitaire, HK Maga de Cotonou, Bénin. yedomonhubert@yahoo.fr
Introduction:
Keloids are abnormal growths of fibrous tissue often seen on dark skin. We studied their clinical, epidemiological and therapeutic aspects in 456 consecutive cases.
Patients And Methods:
This retrospective study covering a 20-year period describes and analyzes all patients seen for keloids during that period.
Results:
The age range of 15-24 year-olds was affected most often (35.72%), and the male/female sex ratio was 0.66. Pruritus was the most frequent symptom (72.23%). The zones at high risk for keloids were: the trunk (chest and abdominal area) (39.57%) and the face (10.65%).The most frequent causes were various sorts of trauma (75%), in descending order of frequency: cutaneous infections, surgical trauma, ulcerating lesions, and burns. The existence of spontaneous keloids remains controversial. Steroid infiltration used alone or with other medication remains the first-line treatment in our study.
Discussion:
Our study confirms the high frequency of keloids in dark skin, especially females. The trunk and face are zones at high risk for keloid formation.
Conclusion:
An underlying trauma must always be sought for keloids on dark skin.
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