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Updated: May 15, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
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Advancing neurosurgery through translational research.

Claire Lacey1, Garnette Sutherland

  • 1Department of Clinical Neurosciences, Division of Neurosurgery, and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

Neurosurgery
|December 21, 2012
PubMed
Summary

Translational research accelerates medical advancements by bridging the gap between laboratory discoveries and clinical practice. Two models, investigator-driven and industry-enabled, facilitate the adoption of new medical technologies.

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Area of Science:

  • Medical Research
  • Biotechnology
  • Health Services Research

Background:

  • The increasing volume of research publications risks obscuring valuable discoveries.
  • Translational research is crucial for integrating novel findings into clinical practice.
  • Effective translation strategies are needed to overcome research-to-practice gaps.

Purpose of the Study:

  • To explore frameworks for maximizing the clinical adoption of research findings.
  • To examine investigator-driven and industry-enabled translational research models.
  • To illustrate industry partnership methods through case studies.

Main Methods:

  • Analysis of two distinct translational research models: investigator-driven and industry-enabled.
  • Case study examination of IMRIS (intraoperative MRI) and neuroArm (surgical robot) partnerships.

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  • Evaluation of strategies for commercializing research innovations.
  • Main Results:

    • Investigator-driven research offers flexibility but is slower; industry-enabled research accelerates development via funding.
    • IMRIS, an investigator-founded company, achieved success after a 7-year development period.
    • The neuroArm project involved selling intellectual property to an established company for global commercialization.

    Conclusions:

    • Translational research models, particularly industry partnerships, are vital for advancing medical practice.
    • Strategic collaborations can expedite the delivery of innovative medical solutions.
    • Successful translation requires tailored approaches based on research goals and commercial potential.