Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioreactor Controls-II01:18

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Introduction.

Advances in experimental medicine and biology·2026
Same author

Magnetoelectric microrobots for spinal cord injury regeneration.

Nature materials·2026
Same author

Membrane Merger Dynamics in Exocytosis and Endocytosis.

Advances in experimental medicine and biology·2026
Same author

Bioinspired ultrasound-driven ultrafast soft microgripper.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

A systematic comparison of membrane, shell, and 3D solid formulations for nonlinear vascular biomechanics.

Journal of the mechanical behavior of biomedical materials·2026
Same author

SonoPIN enables precise, noninvasive, and efficient intracellular delivery of PROTACs.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Tunable self-assembling cellular microarray for single-neutrophil vital and suicidal extracellular traps.

Lab on a chip·2026
Same journal

Precise programmable tumor cell subpopulation sorting <i>via</i> an electromagnetic microfluidic platform.

Lab on a chip·2026
Same journal

Bridging dimensions: combining one- and two-photon 3D printing for microfluidic device fabrication.

Lab on a chip·2026
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
See all related articles

Related Experiment Video

Updated: May 15, 2026

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

Tunable, pulsatile chemical gradient generation via acoustically driven oscillating bubbles.

Daniel Ahmed1, Chung Yu Chan, Sz-Chin Steven Lin

  • 1Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.

Lab on a Chip
|December 21, 2012
PubMed
Summary
This summary is machine-generated.

Researchers created tunable chemical gradients using sound-activated bubbles in a ladder formation. This new method allows for precise control over both static and pulsatile gradient profiles for various applications.

More Related Videos

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels
08:32

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Published on: January 28, 2022

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

Related Experiment Videos

Last Updated: May 15, 2026

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels
08:32

Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels

Published on: January 28, 2022

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

Area of Science:

  • Acoustic manipulation
  • Chemical gradient generation
  • Microfluidics

Background:

  • Chemical gradients are crucial for biological processes and microfluidic applications.
  • Existing methods for generating chemical gradients often lack precise control or dynamic tunability.

Purpose of the Study:

  • To introduce a novel method for generating both static and pulsatile chemical gradients.
  • To demonstrate the tunability of chemical gradient profiles by controlling bubble oscillation amplitude.

Main Methods:

  • Utilizing acoustically activated bubbles arranged in a ladder-like configuration.
  • Employing controlled bubble oscillation amplitudes to influence gradient formation.

Main Results:

  • Successfully generated stable static and dynamic pulsatile chemical gradients.
  • Demonstrated effective tuning of chemical gradient profiles by adjusting acoustic parameters.

Conclusions:

  • Acoustically activated bubbles offer a versatile platform for precise chemical gradient generation.
  • This technique provides a new approach for dynamic control in microfluidic systems and biochemical studies.