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Updated: May 15, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
Published on: May 30, 2011
Perfusion MRI: the five most frequently asked technical questions
Marco Essig1, Mark S Shiroishi, Thanh Binh Nguyen
1Department of Neuroradiology, University of Erlangen-Nuremberg, Maximiliansplatz 1, 91054 Erlangen, Germany. marco.essig@uk-erlangen.de
This article answers common questions about Magnetic Resonance (MR) perfusion imaging in Central Nervous System (CNS) imaging. Overcoming current challenges will enable wider use of this promising neuroimaging technique.
Area of Science:
- Neuroimaging
- Radiology
- Medical Physics
Background:
- Magnetic Resonance (MR) perfusion imaging is increasingly utilized in Central Nervous System (CNS) applications.
- Radiologists frequently encounter challenges in the planning, execution, and interpretation of these studies.
- Standardized approaches are needed to optimize clinical utility.
Purpose of the Study:
- To address the 10 most frequent questions radiologists ask regarding MR perfusion studies in CNS imaging.
- To provide practical guidance for optimizing MR perfusion techniques.
- To facilitate the integration of MR perfusion into routine clinical neuroimaging.
Main Methods:
- This article synthesizes current knowledge and expert consensus on MR perfusion techniques.
- It focuses on practical aspects relevant to clinical workflow.
- Companion article provides further details on specific technical parameters.
Main Results:
- Key questions regarding image acquisition, post-processing, and interpretation are addressed.
- Common pitfalls and their solutions are discussed.
- Guidance is provided for various clinical scenarios.
Conclusions:
- Perfusion MRI is a valuable tool for evaluating stroke, brain tumors, and neurodegenerative diseases.
- Challenges hindering widespread adoption of perfusion MRI are surmountable.
- Integration into modern neuroimaging protocols is feasible and recommended.
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