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Fiber-optic spanner.

Bryan J Black1, Samarendra K Mohanty

  • 1Biophysics and Physiology Group, Department of Physics, University of Texas at Arlington, Texas 76019, USA.

Optics Letters
|December 22, 2012
PubMed
Summary
This summary is machine-generated.

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We developed a fiber-optic spanner for noncontact rotation of microscopic objects like cells. This tool enables controlled cell rotation and translation, advancing applications in imaging and microfluidics.

Area of Science:

  • Biophysics
  • Optical manipulation
  • Microfluidics

Background:

  • Controllable, noncontact rotation of microscopic objects is crucial for applications like tomographic imaging and microfluidic actuation.
  • Existing methods face challenges in precise control and versatility for manipulating biological samples.

Purpose of the Study:

  • To develop a novel fiber-optic spanner for precise, noncontact manipulation of microscopic objects.
  • To demonstrate controlled rotation and translation of smooth muscle cells using the developed device.

Main Methods:

  • Utilized two counterpropagating beams from single-mode optical fibers with a transverse offset to create optical torque.
  • Controlled rotation speed and microfluidic flow by adjusting the power balance of the laser beams.
  • Achieved simultaneous translation and rotation by modulating the power of a single fiber-optic arm.

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Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
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Published on: November 7, 2016

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue
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Published on: October 29, 2012

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Main Results:

  • Successfully demonstrated controlled rotation of optically trapped smooth muscle cells.
  • Showcased the ability to independently control rotation speed and microfluidic flow.
  • Achieved simultaneous translation and rotation of a single trapped cell.

Conclusions:

  • The developed fiber-optic spanner offers a versatile and precise method for noncontact manipulation of microscopic objects.
  • This technology has significant potential for advanced cell analysis, microfluidic device integration, and biomedical applications.