Related Experiment Video
Updated: May 15, 2026

Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
Merkel cell carcinoma arising in a patient with a history of multiple malignancies
Mary L Stevenson1, Sarika Saggar, Bijal Amin
1Department of Dermatology, Columbia University School of Physicians and Surgeons, New York, New York, USA. marylstevenson@gmail.com
Abstract:
Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroendocrine carcinoma of the skin. Although the association between MCC and other primary malignancies has been documented, the mechanism of this association has not been elucidated. We report a case of MCC in a man with a history of multiple primary malignancies and treatment with immunomodulators. This case highlights the increased incidence of other malignancies in patients with MCC and is unique given the number and diversity of primary malignancies found in this patient.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cancers Originate from Somatic Mutations in a Single Cell
Mitogens and the Cell Cycle

