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Enrichment of Native and Recombinant Extracellular Vesicles of Mycobacteria
Published on: December 8, 2023
Cyclo-(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43
Xiang-Yang Liu1, Cheng Wang, Yi-Qiang Cheng
1Department of Biological Sciences, Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, PO Box 413, Milwaukee, WI 53201, USA.
Abstract:
THE TITLE COMPOUND [SYSTEMATIC NAME: (3S,8aS)-3-isopropyl-hexa-hydro-pyrrolo-[1,2-a]pyrazine-1,4-dione], C(10)H(16)N(2)O(2),, is a newly isolated cyclic dipeptide from Burkholderia thailandensis MSMB43. There are two independent mol-ecules in the asymmetric unit. Two C atoms and their attached H atoms in the five-membered ring of one of the mol-ecules are disordered over two sets of sites in a 0.715 (5):0.285 (5) ratio. The two independent mol-ecules have the same configuration and the absolute configurations of the chiral centers were determined based on the observation of anomalous dispersion. In the crystal, two types of N-H⋯O hydrogen bonds link pairs of independent mol-ecules.
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