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Updated: May 15, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Obstructive sleep apnea in children

Manasa Tripuraneni1, Shalini Paruthi, Eric S Armbrecht

  • 1Department of Otolaryngology, Saint Louis University School of Medicine, St Louis, Missouri, USA.

The Laryngoscope
|January 5, 2013
PubMed

Insights

Obese children with obstructive sleep apnea (OSA) experience more severe OSA, behavioral issues, and lower quality of life than normal-weight children. Obesity does not linearly predict OSA severity in pediatric patients.

Area of Science:

  • Pediatric Sleep Medicine
  • Childhood Obesity
  • Behavioral Pediatrics

Background:

  • Obstructive sleep apnea (OSA) is a common sleep disorder in children.
  • The relationship between obesity, OSA severity, behavior, and quality of life in pediatric populations requires further investigation.

Purpose of the Study:

  • To investigate the correlation between obstructive sleep apnea (OSA), obesity, behavior, and quality of life in children.
  • To compare these factors among obese children with OSA, normal-weight children with OSA, and children with primary snoring (PS).

Main Methods:

  • A case-control study involving 73 children diagnosed with OSA via polysomnography.
  • Caregivers completed the Behavior Assessment System for Children (BASC-2) and the OSA Quality-of-Life Survey (OSA-18).
  • Children were categorized into obese with OSA, normal weight with OSA, or primary snoring groups.

Main Results:

  • No linear correlation was found between obesity degree and OSA severity.
  • Obese children with OSA had a significantly higher apnea/hypopnea index compared to normal-weight children with OSA (20.0 vs. 9.0, P = .02).
  • Obese children with OSA exhibited worse quality of life and behavioral scores than normal-weight children with OSA (P = .01 for both).

Conclusions:

  • Obesity does not linearly predict OSA severity in children.
  • Obese children with OSA face greater challenges in terms of OSA severity, behavior, and quality of life.
  • In normal-weight children, OSA or PS did not significantly impact behavior or quality of life scores.
Abstract

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