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Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Gold nanoparticles: an era in bionanotechnology
Deepak Kumar1, Nisha Saini, Nitin Jain
1Shoolini University, School of Pharmaceutical Sciences, Solan H.P, India.
Expert Opinion on Drug Delivery
|January 8, 2013
Summary
Gold nanoparticles are versatile for delivering biomolecules and genes. Their unique optical properties enable sensitive diagnostics, imaging, and targeted therapies.
Area of Science:
- Nanotechnology
- Biomedical Engineering
- Materials Science
Background:
- Gold nanoparticles (AuNPs) are increasingly utilized for biomolecule and gene delivery.
- They offer potential for highly sensitive diagnostic and imaging applications.
Purpose of the Study:
- This review covers the synthesis, properties, and diverse applications of gold nanoparticles.
- It highlights their role in drug delivery, diagnostics, imaging, and photothermal therapy.
Main Methods:
- The review synthesizes information on the historical development and synthesis of gold nanoparticles.
- It examines their optical properties, including size- and shape-dependent color variations and resonance light emission.
- Applications as probes for sensing and imaging biomolecules and cells are discussed.
Main Results:
- Gold nanoparticles exhibit unique optical properties influenced by their size, shape, and surface characteristics.
- These properties enable their use as effective probes for sensing and imaging various biological targets.
- Their potential as biosensors in living cells is also noted.
Conclusions:
- Gold nanoparticles present a valuable platform for the effective delivery of biomolecules and genes.
- Their unique optical and physical properties support broad applications in nanomedicine.
