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Updated: May 15, 2026
Transvaginal Mesh Insertion in the Ovine Model
Published on: July 27, 2017
Evaluation of fixation of expandable implants in the mandibles of ovariectomized sheep
Jian-Rui Xiao1, De-Hua Li, Yu-Xuan Chen
1Department of Stomatology, PLA 252 Hospital, Baoding, China.
Purpose:
This study aimed to investigate the effects of an expandable implant (EI) in ovariectomized sheep.
Methods:
The EI and taper implant (control group) were produced and placed in mandibles of ovariectomized sheep. Twelve weeks after implantation, resonance frequency analysis, biomechanical tests, histomorphometry, and micro-computed tomography were applied to detect the osseointegration in the 2 groups.
Results:
The implant stability quotient values, maximal pullout forces, and bone-implant contact (BIC) were 60.3 ± 7.9, 511.0 ± 18.7 N, and 53.14% ± 4.56%, respectively, in the EI group and 58.3 ± 8.9, 394.5 ± 54.5 N, and 46.85% ± 5.04%, respectively, in the control group. There was no significant difference between the 2 groups in implant stability quotient values (P > .05); however, in the EI group the maximal pullout force and BIC were increased significantly (P < .05 and P < .01, respectively). Micro-computed tomography analysis showed that the bone volume/total volume ratio and trabecular number increased significantly (P < .01) and trabecular separation decreased significantly (P < .05) in the EI group.
Conclusions:
EI could improve osseointegration in osteoporosis after 12 weeks of implantation by increasing BIC around the implant and by supplying an extra osseointegration surface.
