Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Influence of visual design on young users' attention to digital museum homepages: an eye-tracking study.

Scientific reports·2026

Same author

The CoNi@C/Mo<sub>1.33</sub>C i-MXene Derived from Novel (Mo<sub>2/3</sub>R<sub>1/3</sub>)<sub>2</sub>GaC (R = Dy, Ho, Er, Tm, and Lu) Nanolaminations for Electrochemical Application in Electrocatalytic Hydrogen Evolution and Supercapacitance.

Small (Weinheim an der Bergstrasse, Germany)·2024

Same author

Rare-Earth (R) In-Plane Ordering in Novel (Mo, R, Nb)<sub>4</sub>AlC<sub>3</sub> Quinary o-MAX Nanolaminates and their 2D Derivatives.

Advanced materials (Deerfield Beach, Fla.)·2024

Same author

In-Plane Chemical Ordering (Mo<sub>2/3</sub>R<sub>1/3</sub>)<sub>2</sub>AlB<sub>2</sub> (R = Tb, Dy, Ho, Er, Tm, and Lu) i-MAB Phases and their Two-Dimensional Derivatives (MBene): Synthesis, Structure, Magnetic, and Supercapacitor Performance.

Small (Weinheim an der Bergstrasse, Germany)·2023

Same author

A universal route to efficient non-linear response via Thomson scattering in linear solids.

National science review·2023

Same author

Segmentation of multi-regional skeletal muscle in abdominal CT image for cirrhotic sarcopenia diagnosis.

Frontiers in neuroscience·2023

Search research articles

Related Experiment Video

Updated: May 15, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

Highly efficient construction of oriented sandwich structures for surface-enhanced Raman scattering.

Hongyun Guo¹, Weiqing Xu, Ji Zhou

¹State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130012, People's Republic of China.

|January 10, 2013

Summary

Researchers developed a novel method for fabricating highly efficient sandwich surface-enhanced Raman scattering (SERS) substrates. This technique achieves nearly 100% hot spot formation, significantly amplifying SERS signals for improved detection capabilities.

More Related Videos

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications

Published on: June 16, 2023

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Published on: November 17, 2023

Related Experiment Videos

Last Updated: May 15, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications

Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications

Published on: June 16, 2023

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Published on: November 17, 2023

Area of Science:

Nanotechnology
Materials Science
Spectroscopy

Background:

Fabricating sandwich surface-enhanced Raman scattering (SERS) substrates often suffers from low achievement and inconsistent hot spot formation.
Oriented assembly of nanoparticles is crucial for enhancing SERS signal amplification and reproducibility.

Purpose of the Study:

To address the challenge of low achievement in fabricating sandwich SERS substrates.
To develop a method for the oriented assembly of metal nanoparticles (NPs) on a nanoprism array for improved SERS performance.

Main Methods:

Fabrication of a periodic hexagonal array of metal nanoprisms via vacuum deposition on a nanosphere-templated substrate.
Utilizing 1,4-benzenedithiol (1,4-BDT) as linkers for selective adsorption and oriented immobilization of the second-layer metal NPs.
Characterization using extinction spectroscopy and atomic force microscopy, with SERS enhancement evaluation under various excitation wavelengths.

Main Results:

Achieved highly efficient sandwich SERS substrates with oriented assembly of metal NPs.
Demonstrated a near 100% achievement of 'hot spots' across all metal nanoprisms.
Observed a tenfold amplification of SERS signals due to the optimized sandwich structure.

Conclusions:

The developed method offers a simple, efficient, and reproducible approach for fabricating high-performance sandwich SERS substrates.
The oriented assembly strategy significantly enhances SERS signal amplification and hot spot generation.
This work holds importance for advancing SERS substrate research and developing novel plasmonic devices.