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Published on: August 31, 2018
A new spatane diterpenoid from the cultured soft coral Sinularia leptoclados
Tsung-Chang Tsai1, Yu-Jen Wu, Jui-Hsin Su
1Department of Superintendent, Antai Medical Care Cooperation Antai Tian-Sheng Memorial Hospital, Pingtung 92842, Taiwan. a088186@mail.tsmh.org.tw
Abstract:
A new spatane diterpenoid, leptoclalin A (1), along with two previously reported known norcembranoid diterpenes (2 and 3), were isolated from a cultured soft coral Sinularia leptoclados. The structures were determined by extensive spectroscopic analyses and by comparison with the spectral data of related known compounds. Metabolite 1 is rarely found in spatane skeletons reported from soft corals. In addition, compound 1 exhibited weak cytotoxicity towards human tumor cell lines T-47 D and K-562.
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