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Updated: May 15, 2026

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Antiviral and antibacterial polyurethanes of various modalities
Daewon Park1, Alyssa M Larson, Alexander M Klibanov
1Department of Bioengineering, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 80045, USA. daewon.park@ucdenver.edu
Abstract:
We have prepared and characterized a new polyurethane-based antimicrobial material, N,N-dodecyl,methyl-polyurethane (Quat-12-PU). It exhibits strong antiviral and antibacterial activities when coated (as an organic solution or an aqueous nanosuspension) onto surfaces and antibacterial activity when electrospun into nanofibers. Quat-12-PU surfaces are able to kill airborne Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria, as well as inactivate the enveloped influenza virus (but not the non-enveloped poliovirus).
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