Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Population data and a fourth allele for equine complement component 3 (C3).

A T Bowling1, S Dileanis

  • 1Serology Laboratory, School of Veterinary Medicine, University of California, Davis 95616.

Animal Genetics
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Letters.

The Journal of heredity·2019
Same author

An international parentage and identification panel for the domestic cat (Felis catus).

Animal genetics·2007
Same author

Genetic variation in Przewalski's horses, with special focus on the last wild caught mare, 231 Orlitza III.

Cytogenetic and genome research·2004
Same author

The second generation of the International Equine Gene Mapping Workshop half-sibling linkage map.

Animal genetics·2003
Same author

The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21.

Animal genetics·2001
Same author

Equine dinucleotide repeat loci LEX071 through LEX078.

Animal genetics·2000
Same journal

Genome-Wide Association Study and Genomic Prediction for Maximum Litter Size in Sows.

Animal genetics·2026
Same journal

Transcriptomic Analysis Reveals Multilayer Regulation Underlying Development and Pregnancy in the Malayan Pangolin.

Animal genetics·2026
Same journal

Gestational Feed Restriction Induces Differential Expression of Novel Long Non-Coding RNAs in Offspring Skeletal Muscle.

Animal genetics·2026
Same journal

A NECAP1 Nonsense Variant is Associated With Leukoencephalomyelopathy With Oligodendroglial Dysplasia in a Belgian Malinois With Spinocerebellar Ataxia.

Animal genetics·2026
Same journal

Enrichment Analysis of Differentially Expressed Genes During Feather Regeneration in Landes Geese (Anser anser).

Animal genetics·2026
Same journal

Multi-Omics Analysis Reveals Impacts of SCARB1, TYR, and TYRP1 Knockouts on Pigmentation and Metabolic Pathways in Oujiang Color Common Carp.

Animal genetics·2026
See all related articles

Researchers identified a new C3 allele (C34) in horse serum using agarose gel electrophoresis. This finding expands the known C3 polymorphism in horses, with population data presented for various breeds.

Area of Science:

  • Animal genetics
  • Biochemistry
  • Veterinary science

Background:

  • The complement component 3 (C3) is a crucial protein in the innate immune system.
  • C3 polymorphism in equines has been previously characterized, with three known alleles.

Purpose of the Study:

  • To investigate the C3 polymorphism in equine serum or plasma.
  • To identify and characterize novel C3 alleles in horses.
  • To present population data for C3 alleles across different equine breeds.

Main Methods:

  • Agarose gel electrophoresis was employed to analyze equine serum or plasma.
  • Protein staining following acid protein fixation was used for C3 visualization.
  • Genetic typing was performed for C3 alleles.

Related Experiment Videos

Main Results:

  • A fourth allele, designated C34, was discovered in addition to the previously known C31, C32, and C33 alleles.
  • The C3 polymorphism was successfully diagnosed using the described electrophoretic and staining methods.
  • Population data were collected and analyzed for 25 domestic horse breeds and Equus przewalskii.

Conclusions:

  • The C3 polymorphism in horses is more diverse than previously understood, with the identification of the C34 allele.
  • The diagnostic method utilizing agarose gel electrophoresis is effective for C3 allele identification in equine populations.
  • The presented population data provide valuable insights into the genetic diversity of C3 across various horse breeds.