Related Experiment Video
Updated: May 15, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Periodontal disease and systemic complications
Rui Vicente Oppermann1, Patricia Weidlich, Marta Liliana Musskopf
1Department of Periodontology, School of Dentistry, Univ Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. ruioppermann@gmail.com
Brazilian Oral Research
|January 16, 2013
Summary
Periodontal diseases are infectious inflammatory conditions influenced by systemic factors. Prevention and treatment are crucial for oral and overall health, as these diseases can impact systemic conditions.
Area of Science:
- Oral health
- Systemic health
- Inflammatory diseases
Background:
- Periodontal diseases involve interactions between oral biofilms and host inflammatory responses.
- These conditions are increasingly recognized as systemic, affecting and being affected by the body's overall health.
- Existing evidence links smoking and diabetes mellitus to periodontal disease due to shared inflammatory pathways.
Purpose of the Study:
- To explore the systemic implications of periodontal diseases.
- To highlight the bidirectional relationship between periodontal health and systemic conditions.
- To emphasize the importance of periodontal disease prevention and treatment for overall well-being.
Main Methods:
- Review of current scientific evidence on periodontal disease and systemic interactions.
- Analysis of established and potential associations between periodontal disease and systemic derangements.
- Focus on inflammatory pathways linking oral health to systemic conditions.
Main Results:
- Periodontal diseases are systemic conditions, modulated by and influencing the body's systems.
- Smoking and diabetes mellitus are confirmed risk factors and are influenced by periodontal disease.
- Associations with obesity, hormonal changes, cardiovascular disease, and pregnancy outcomes require further research.
Conclusions:
- Periodontal disease prevention and treatment are vital for managing systemic health.
- Recognizing periodontal disease as a systemic condition is essential for comprehensive patient care.
- Further research is needed to fully understand the systemic repercussions of periodontal disease.
Related Concept Videos
01:27The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
01:22Complications of Diabetes Mellitus
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:25Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
01:21Tooth Anatomy
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
01:15Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...