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Updated: May 15, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Using d-dimer to diagnose painless acute aortic dissection: a case report.
Caroline Barniol1, Baptiste Vallé, Emilie Dehours
1Pôle de Médecine d'Urgence, Hôpitaux Universitaires de Toulouse, CHU Purpan, TSA 40031, 31059 Toulouse Cedex 9, France.
Acute aortic dissection can present atypically, with syncope and arm weakness mimicking other conditions. Elevated D-dimer levels are crucial diagnostic indicators for this cardiovascular emergency.
Area of Science:
- Cardiovascular Medicine
- Emergency Medicine
- Diagnostic Imaging
Background:
- Aortic dissection is a life-threatening condition often presenting with chest pain.
- Clinical manifestations can be diverse and non-specific, complicating early diagnosis.
Observation:
- A 66-year-old male presented with syncope and left-arm weakness, without typical chest pain.
- Physical examination revealed bilateral jugular vein distension; ECG and chest X-ray were normal.
- Elevated D-dimer levels (>4000 ng/mL) were detected, prompting further investigation.
Findings:
- A thoracic aortic dissection was confirmed via chest computed tomography angiogram.
- The case highlights the diagnostic challenge posed by atypical presentations of aortic dissection.
Implications:
- Integrating clinical signs with D-dimer testing improves the diagnosis of acute aortic dissection.
- Utilizing a pretest probability score for D-dimer, similar to pulmonary embolism protocols, may aid emergency physicians.
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