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The ultra-high risk concept-a review
Alison R Yung1, Barnaby Nelson
1Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia. alison.yung@manchester.ac.uk
Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
|January 19, 2013
Summary
Identifying individuals at imminent risk of psychotic disorder remains crucial. Interventions like psychological treatments and fish oil show promise, comparable to antipsychotics, for those at high risk.
Area of Science:
- Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Over the past two decades, efforts have focused on identifying individuals at imminent risk of psychotic disorder.
- High-risk criteria have been established, and while the rate of psychosis onset has recently declined, identified individuals remain at significantly elevated risk compared to the general population.
Purpose of the Study:
- To evaluate the effectiveness of interventions for individuals identified as high-risk for psychosis.
- To explore future research directions in psychosis risk assessment and intervention.
Main Methods:
- Review of intervention studies conducted on individuals meeting high-risk criteria for psychosis.
- Analysis of existing data on psychosis onset rates and risk factors.
Main Results:
- Psychological treatments and fish oil have demonstrated effectiveness comparable to antipsychotic medications in high-risk individuals.
- Despite a recent decline, individuals identified by high-risk criteria maintain a substantially greater risk of psychosis than the general population.
Conclusions:
- Psychological interventions and fish oil represent viable alternatives to antipsychotics for individuals at imminent risk of psychosis.
- Further research is warranted to refine psychosis risk factors, explore non-psychotic outcomes, and assess the implications of formalizing high-risk criteria into a diagnosis.
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