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Updated: May 15, 2026
08:03
Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
Published on: April 18, 2013
A tutorial on the application of ion-selective electrode potentiometry: an analytical method with unique qualities,
Ernő Lindner1, Bradford D Pendley
1Department of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, United States. elindner@memphis.edu
Analytica Chimica Acta
|January 19, 2013
Summary
Ion-selective potentiometry offers a simple method for measuring ions in complex samples. Modern ion-selective electrodes (ISEs) enable precise trace analysis at micro and nanomolar levels.
Area of Science:
- Analytical Chemistry
- Electrochemistry
Background:
- Ion-selective potentiometry is a valuable analytical technique for determining ionic concentrations.
- Recent advancements have significantly enhanced the performance of ion-selective electrodes (ISEs).
Purpose of the Study:
- To review the fundamental principles of ion-selective potentiometry.
- To outline practical considerations for using ISEs with real samples.
- To discuss statistical evaluation of results compared to other methods.
Main Methods:
- Review of fundamental potentiometric principles.
- Discussion of practical aspects of ISE sensor utilization.
- Comparative analysis of statistical evaluation methods.
Main Results:
- Improved selectivity and lower detection limits of ISEs.
- Feasibility of trace analysis in micro and nanomolar concentrations.
- Practical guidelines for real-world sample analysis.
Conclusions:
- Ion-selective potentiometry is a powerful tool for ionic analysis.
- Advances in ISEs allow for highly sensitive and selective measurements.
- This tutorial provides a comprehensive guide for researchers and practitioners.
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