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Published on: November 6, 2019
African American ethnicity as a risk factor for respiratory complications following adenotonsillectomy
Linda Horwood1, Lily H P Nguyen, Karen Brown
1Departments of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Canada.
Insights
African American children undergoing adenotonsillectomy (T&A) face nearly double the risk of major respiratory complications. This highlights ethnicity as a crucial factor for surgical risk assessment in pediatric patients.
Area of Science:
- Pediatric Surgery
- Otolaryngology
- Health Disparities
Background:
- Adenotonsillectomy (T&A) is a common pediatric procedure.
- Understanding risk factors for perioperative complications is crucial for patient safety.
Purpose of the Study:
- To determine if African American ethnicity is an independent risk factor for major respiratory complications after T&A.
Main Methods:
- Retrospective cohort study of children (0-18 years) undergoing T&A.
- Used sickle cell test (TestSC) as a proxy for African American ethnicity.
- Analyzed association between ethnicity and major perioperative respiratory complications.
Main Results:
- 12.5% of children experienced major respiratory complications.
- African American children (identified by TestSC) had a significantly higher risk (adjusted odds ratio, 1.82).
- Younger age, lower weight-for-age z scores, obstructive sleep apnea, and comorbidities were also risk factors.
Conclusions:
- African American ethnicity is an independent risk factor for major respiratory complications post-T&A.
- Clinicians should consider ethnicity in preoperative risk assessment for T&A.
- This finding may contribute to reducing health disparities in pediatric surgical outcomes.
Objective:
To evaluate whether African American ethnicity is a risk factor for major respiratory complications following adenotonsillectomy (T&A).
Design:
Retrospective cohort study.
Setting:
A Canadian tertiary care center. PATIENTS Children aged 0 to 18 years who underwent T&A at our institution from 2002 to 2006 with planned or unplanned postoperative admissions.
Main Outcome Measures:
We evaluated the association between ethnicity and our main outcome measure, major perioperative respiratory complications of T&A. Parental report of ethnicity was available for 23% of our cohort. At our institution, African American children undergo a routine preoperative sickle cell test (TestSC). Data on TestSC were included for all children. We established that having a TestSC was an accurate proxy for African American ethnicity (sensitivity, 96%; specificity, 93%; positive predictive value, 77%; negative predictive value, 99%).
Results:
Seventy-four of 594 children experienced major respiratory complications (12.5%). Compared with children who did not have major respiratory complications, those who did had a TestSC (P = .01), were 2 years or younger (P < .001) and had lower weight-for-age z scores (P = .04), moderate to severe obstructive sleep apnea (P = .003), and comorbidities (P < .001). When controlling for these variables in a multivariate analysis, children of African American ethnicity (TestSC used as a proxy) were at higher risk of having major perioperative respiratory complications (adjusted odds ratio, 1.82 [95% CI 1.05-3.14]) (P = .003).
Conclusions:
Children of African American ethnicity (TestSC used as a proxy) are nearly twice as likely to experience major respiratory complications related to T&A. Ethnicity may be an additional independent risk factor for clinicians to consider when planning for T&A.
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