Related Experiment Video
Updated: May 15, 2026
09:32
Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
Published on: April 12, 2019
Sequential [6+2], [2+2], and [3+2] annulations for rapid assembly of multiple fragments
Velisoju Mahendar1, Hideaki Oikawa, Hiroki Oguri
1Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan.
Chemical Communications (Cambridge, England)
|January 19, 2013
Abstract:
Assembly of four components through sequential [6+2], [2+2], and [3+2] annulations on an azulenone manifold allows for five-step access to a natural product-inspired scaffold with exquisite control of the ten consecutive stereocenters. X-ray analysis was used to define the spatial arrangement of the three fragments and functional groups on this rigid scaffold.
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