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Letter to the editor: Application of dapsone 5% gel in a patient with dermatitis herpetiformis

Marc Z Handler1, Anna H Chacon, Michael I Shiman

  • 1University of Miami Miller School of Medicine - Department of Dermatology & Cutaneous Surgery, Miami, FL 33136.

Journal of Dermatological Case Reports
|January 19, 2013
PubMed
Abstract

No abstract available in PubMed .

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Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...

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