Related Experiment Video
Updated: May 15, 2026

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
Published on: March 22, 2022
Integrated quality control: implementation and validation of instrument function checks and procedural controls for a
Paul D'Orazio1, Sohrab Mansouri
1Research and Development, Instrumentation Laboratory, 180 Hartwell Road, Bedford, MA 01730, USA. pdorazio@ilww.com
Abstract:
In this article, the process used to develop and validate an integrated quality-control system for a cartridge-based, point-of-care system for critical care analysis is outlined. Application of risk management principles has resulted in a quality control system using a combination of statistical quality control with onboard reference solutions and failure pattern recognition used to flag common failure modes during the analytical phase of the testing process. A combination of traditional external quality control, integrated quality control to monitor ongoing instrument functionality, operator training, and other laboratory-implemented monitors is most effective in controlling known failure modes during the testing process.
Related Concept Videos
Automated Microbial Diagnostics
Introduction to Statistical Process Control
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Health Information Technology and Healthcare Information System
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
In Vitro Drug Release Testing: Overview, Development and Validation
Control Systems
At the heart...