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A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
Published on: March 9, 2017
Metal coordination in photoluminescent sensing
Zhipeng Liu1, Weijiang He, Zijian Guo
1State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
Chemical Society Reviews
|January 22, 2013
Summary
Coordination chemistry enables the development of advanced photoluminescent probes for detecting metal ions, anions, and biomolecules. These metal complexes offer unique luminescence properties for sensitive and selective chemical sensing applications.
Area of Science:
- Coordination Chemistry
- Photoluminescence
- Chemical Sensing
Background:
- Metal coordination to organic dyes alters optical properties, enabling detection of metal ions.
- Luminescent lanthanide (Ln3+) and transition metal complexes offer unique photophysical properties for probe development.
Purpose of the Study:
- To review design principles and coordination chemistry of metal probes.
- To discuss rationales for turn-on and ratiometric probe design.
- To highlight progress in photoluminescent probes for essential/toxic metal cations and biomolecules.
Main Methods:
- Exploration of photoluminescent probes based on Photoinduced Electron Transfer (PeT), Photoinduced Charge Transfer (PCT), Excited-State Intramolecular Proton Transfer (ESIPT), Förster Resonance Energy Transfer (FRET), and excimer formation.
- Analysis of phosphorescent probe design using Ln3+ and d6, d8, d10-metal complexes.
- Review of sensing behaviors and design approaches for various analytes.
Main Results:
- Metal complexes exhibit superior luminescence properties (high quantum yield, large Stokes shift, long emission wavelength) compared to organic dyes.
- Design strategies for turn-on and ratiometric probes are detailed.
- Recent advancements in probes for essential/toxic metal cations and biorelated anions/neutral molecules are surveyed.
Conclusions:
- Coordination chemistry is crucial for designing sophisticated photoluminescent probes.
- Metal complex-based probes offer versatile platforms for detecting a wide range of chemical species.
- These probes have significant potential in environmental monitoring and biomedical diagnostics.
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