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[Epidemiological characteristics of Mycoplasma pneumoniae pneumonia in children]
Li-Qin Ke1, Feng-Mei Wang, Yin-Jie Li
1Department of Pneumology, Yuying Children's Hospital Affiliated to Wenzhou Medical College, Wenzhou, Zhejiang, China.
Objective:
To study the epidemiological characteristics of Mycoplasma pneumoniae pneumonia (MPP) in children, and to provide a basis for diagnosis and treatment.
Methods:
The serum level of Mycoplasma pneumoniae antibody IgM (MP-IgM) was measured by enzyme-linked immunosorbent assay for 3156 hospitalized children with confirmed community acquired pneumonia from February 2011 to January 2012. The antigens of seven respiratory viruses were detected in the nasopharyngeal secretions of children with MPP.
Results:
MP-IgM was detected in 427 of the 3156 patients, with a positive rate of 13.53%. The infection rate in female patients was significantly higher than in male patients (16.30% vs 11.70%; P<0.01). The MP-IgM detection rates were 3.6%, 12.5%, 19.2%, and 24.4% in children aged under 1 year, 1-3 years, 3-6 years and 6-14 years respectively (P<0.01), and the total MP-IgM detection rate in children aged under 3 years was significantly lower than in children over 3 years (P<0.01). The MP-IgM detection rate varied with the seasons and was significantly higher in summer and autumn than in winter and spring (19.18% vs 9.61%; P<0.01). Of the 427 MP-IgM-positive children, 60 (14.1%) were infected with respiratory viruses, and the highest proportion of which was respiratory syncytial virus.
Conclusions:
MPP is sporadic throughout the whole year, with a higher incidence in summer and autumn. MPP occurs mostly in preschool and school-age children, and there is mixed infection of MP and respiratory viruses.
Insights
Mycoplasma pneumoniae pneumonia (MPP) is more common in girls and children over 3 years old, with higher rates in summer and autumn. Co-infections with respiratory viruses, like RSV, are also observed in pediatric MPP cases.
Area of Science:
- Pediatric infectious diseases
- Respiratory medicine
- Epidemiology
Context:
- Community-acquired pneumonia (CAP) is a significant cause of childhood illness.
- Mycoplasma pneumoniae (MP) is a common bacterial pathogen responsible for atypical pneumonia in children.
- Understanding the epidemiological patterns of MP pneumonia (MPP) is crucial for effective public health strategies.
Purpose:
- To investigate the epidemiological characteristics of Mycoplasma pneumoniae pneumonia (MPP) in hospitalized children.
- To identify risk factors and seasonal trends associated with MPP.
- To provide data to inform the diagnosis and treatment of pediatric MPP.
Summary:
- A study of 3156 children with CAP found a 13.53% positive rate for Mycoplasma pneumoniae IgM antibodies (MP-IgM).
- MPP incidence was higher in females, children aged 3-14 years, and during summer and autumn months.
- Co-infections with other respiratory viruses, notably RSV, were identified in 14.1% of MPP cases.
Impact:
- This research highlights key demographic and seasonal factors influencing MPP in children.
- Findings can aid clinicians in suspecting and diagnosing MPP, particularly during peak seasons.
- Understanding co-infection patterns can guide empirical treatment decisions for pediatric pneumonia.
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