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Related Experiment Video

Updated: May 14, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Dose correction in lung for HDR breast brachytherapy.

Eric Slessinger¹, Eric Pepin, Qingya Zhao

¹Indiana University Simon Cancer Center, Indiana University School of Medicine, Indiana.

Journal of Contemporary Brachytherapy

|January 26, 2013

Summary

Dosimetry for Accelerated Partial Breast Irradiation (APBI) using Iridium-192 shows lung tissue significantly alters radiation dose. Current treatment planning systems do not accurately predict these effects, necessitating new models for lung dose estimation.

Keywords:

HDR dosimetry lung partial breast irradiation

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Published on: March 11, 2021

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Last Updated: May 14, 2026

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Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

Medical Physics
Radiation Oncology
Brachytherapy

Background:

Accelerated Partial Breast Irradiation (APBI) is a brachytherapy technique using Iridium-192 (Ir-192).
Accurate dose calculation is crucial for effective treatment and minimizing side effects.
The dosimetric impact of low-density tissues, such as lung, is not well understood in APBI.

Purpose of the Study:

To evaluate the dosimetric impact of lung tissue in Ir-192 APBI.
To compare measured dose distributions in low-density material with predictions from a commercial treatment planning system.

Main Methods:

A brachytherapy balloon was placed in a water tank simulating breast tissue.
Ionization measurements were taken in solid water and cork phantoms at various depths.
Dose measurements in cork were compared to solid water and treatment planning system predictions.

Main Results:

Lower doses were observed near the cork/solid water interface due to backscatter.
Higher doses were measured beyond 1 cm in cork, increasing with depth up to 15% at 9 cm.
The commercial treatment planning system failed to predict these observed dose variations.

Conclusions:

Iridium-192 HDR dose in low-density media like cork differs significantly from unit-density media.
Current brachytherapy planning systems do not account for these dose discrepancies.
Empirical models based on measurements are needed to estimate lung dose in HDR breast brachytherapy.