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Published on: December 6, 2016
Adenotonsillectomy for sleep-disordered breathing in a predominantly obese pediatric population
David H Burstein1, Alison Jackson, Jeremy Weedon
1Division of Pediatric Otolaryngology, SUNY Downstate Medical Center and Kings County Hospital Center, 450 Clarkson Avenue, Box 126, Brooklyn, NY 11203, United States.
Insights
Adenotonsillectomy (T&A) significantly improved apnea-hypopnea index (AHI) in children with sleep-disordered breathing compared to no surgery. Some untreated children showed improvement, but T&A offered greater benefits.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Respiratory Physiology
Background:
- Sleep-disordered breathing (SDB) is common in children.
- Adenotonsillar hypertrophy is a primary cause of pediatric SDB.
- Adenotonsillectomy (T&A) is a common treatment for pediatric SDB.
Purpose of the Study:
- To evaluate the efficacy of adenotonsillectomy (T&A) for pediatric sleep-disordered breathing.
- To compare T&A outcomes with the natural history of SDB in untreated children.
Main Methods:
- Retrospective chart review of children (1-12 years) with positive polysomnography (PSG).
- Matched pairs of T&A-treated and untreated children were compared.
- Evaluations included clinical assessment score (CAS-15), follow-up PSG, and Child Behavior Checklist (CBCL).
Main Results:
- T&A group showed greater median improvement in apnea-hypopnea index (AHI) (10.3 vs. 6.5).
- T&A patients had significantly lower CAS-15 and CBCL scores.
- Younger age, higher initial AHI, and initial apnea index predicted AHI improvement in T&A patients.
Conclusions:
- Adenotonsillectomy is more effective than no surgery in reducing AHI for pediatric SDB.
- While some untreated children experienced AHI improvement, T&A yielded superior clinical outcomes.
- T&A demonstrated significant benefits in reducing SDB severity and improving behavioral aspects.
Objectives:
To determine the efficacy of adenotonsillectomy (T&A) in the treatment of pediatric sleep-disordered breathing, and to determine the natural history in untreated children.
Methods:
The charts of children aged 1-12 who underwent polysomnography (PSG) between 1/2006 and 6/2009 were reviewed to identify children with positive studies. Children not treated by T&A were recruited and matched by age, time since initial PSG, and apnea-hypopnea index (AHI) to children who underwent T&A. All participants were evaluated by a clinical assessment score (CAS-15), follow-up PSG, and the Child Behavior Checklist (CBCL).
Results:
Sixteen matched pairs completed the study. Ten (63%) T&A patients were overweight or obese compared with 14 (88%) untreated patients. There was a greater median improvement in AHI in the surgical group compared to the nonsurgical group (10.3 vs. 6.5, p=0.044). Although the T&A children were more likely to have a follow-up AHI<5 (81% vs. 69%) and <1 (44% vs. 25%), these results were not significant. The T&A group had significantly lower mean (SD) scores on the CAS-15 [8.9(6.1) vs. 29.4(16.2), p<0.001] and the CBCL total problem score [43.9(8.7) vs. 58.9(13.0), p<0.001]. Younger age at presentation (rho=-0.76, p<0.001), initial AHI (0.87, p<0.001), and initial AI (0.63, p=0.05) were correlated with change in AHI among T&A subjects.
Conclusions:
T&A was more effective in reducing AHI than no surgery. Median AHI improved in the nonsurgical group, and 4/16 (25%) untreated patients were cured (AHI<1).
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