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Updated: May 14, 2026
Targeted DNA Methylation Analysis by Next-generation Sequencing
Published on: February 24, 2015
Simultaneous profiling of multiple gene-methylation loci by electrochemical methylation-specific ligase detection
Zong Dai1, Ting Cai, Wenyuan Zhu
1School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, P. R. China. daizong@mail.sysu.edu.cn
Abstract:
A novel method of electrochemical methylation-specific ligation detection reaction is first presented for simultaneous evaluation of multiple gene-methylation loci in a single-tube experiment without PCR amplification or restriction enzyme reaction.
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