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Related Experiment Video

Updated: May 14, 2026

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
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Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

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Vascular stents with rationally-designed surface patterning.

Shannon C Gott1, Benjamin A Jabola, Guanshui Xu

  • 1Mechanical Engineering Department, University of California-Riverside, Riverside, CA 92521 USA. sgott@engr.ucr.edu

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|February 1, 2013
PubMed
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Researchers are developing advanced vascular stents with nanoscale surface patterns to reduce adverse reactions. This approach aims to improve stent performance and potentially replace drug-based treatments.

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Medical Devices

Background:

  • Vascular stenting can cause adverse physiological responses.
  • Current stents often rely on pharmacological interventions to mitigate these issues.
  • There is a need for innovative stent designs that address these limitations.

Purpose of the Study:

  • To report progress on next-generation vascular stents with nanoscale surface topography.
  • To explore the fabrication of titanium stents with precisely engineered surface features.
  • To evaluate the mechanical properties and potential of these rationally designed stents.

Main Methods:

  • Patterning of deep sub-micrometer features on titanium substrates.
  • Fabrication of cylindrical stents from micromachined planar titanium.

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Related Experiment Videos

Last Updated: May 14, 2026

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
06:55

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

Published on: October 26, 2016

4D Printed Bifurcated Stents with Kirigami-Inspired Structures
06:52

4D Printed Bifurcated Stents with Kirigami-Inspired Structures

Published on: July 25, 2019

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
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Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

  • Mechanical testing and finite element modeling of stent devices.

    • Main Results:

    • Demonstrated advances in creating nanoscale surface features on titanium.
    • Successfully fabricated cylindrical stents from patterned titanium substrates.
    • Assessed the mechanical performance of the novel stent designs through testing and modeling.

    Conclusions:

    • Rationally designed nanopatterning on stent surfaces shows promise for mitigating adverse responses.
    • These advancements are key steps towards a new paradigm for vascular stents.
    • Surface nanopatterning offers a physical approach to complement or replace pharmacological therapies.