Massive gastrointestinal hemorrhage in an immunosuppressed man due to gastric Kaposi's sarcoma

Kaposi's sarcoma, a neoplasm that occurs in immunocompromised patients and people of Mediterranean origin, usually presents with skin lesions. However, extracutaneous lesions are common, and the gastrointestinal tract is often involved. We report the case of an iatrogenically immunosuppressed patient who presented with a massive upper gastrointestinal hemorrhage that was caused by Kaposi's sarcoma of the stomach. Kaposi's sarcoma in the setting of immunosuppression and the gastrointestinal manifestations of this disease are reviewed.