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Updated: May 14, 2026
Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
[Assessment of retinal ganglion cells thickness in high myopia]
Michał Szumiński1, Alina Bakunowicz-Łazarczyk
1Klinika Okulistyki Dzieciecej z Ośrodkiem Leczenia Zeza, Uniwersyteckiego Dzieciecego Szpitala Klinicznego w Białymstoku. mike-sz@mp.pl
Purpose:
Studies on glaucoma markers have shown that assessment of thickness macular ganglion cell complex plays an important role in diagnosis of early stage open-angle glaucoma. There are no available data on thickness in ganglion cell complex in high myopic patients. We investigate thickness of macular ganglion cell complex in children with high myopia.
Material And Methods:
38 children (aged from 9 to 19 years), with high myopia (over -6.00 D) underwent full ophthalmological examination, including SD-OCT of the macula and optic disc. The reference group consisted of 38 emmetropic or slightly hyperopic children aged from 8 to 18 years old.
Results:
Superior and interior ganglion cell complex (GCC) thickness were significantly lower in high myopic group compared to reference group: p < 0.01, respectively for GCC Sup. median was 90 microm (range 67-108.5) and 95 microm (range 80-105.5); for GCC Inf. median was 91 microm (range: 67-109.5) and 98 microm (range 85-109). Positive correlation between GCC and Total RNFL was found.
Conclusions:
In children with high myopia thinning of macular ganglion cell complex and retinal nerve fiber layer of the optic disc was found. These changes may be responsible for higher suspectibility of developing open-angle glaucoma in high myopic eyes. macular ganglion cell complex, high myopia, spectral optical coherence tomography.
