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Diarrhoea due to pancreatic diseases
1Division of Gastroenterology, Department of Medicine, Maimonides Medical Center, State University of New York, 2211 Emmons Ave, Brooklyn, NY 11235, USA.
Best Practice & Research. Clinical Gastroenterology
|February 7, 2013
Summary
Pancreatic diseases like pancreatitis and cancer disrupt digestive enzyme production, leading to malabsorption and diarrhea. Over 90% of pancreatic tissue damage is typically required to cause this digestive issue.
Area of Science:
- Gastroenterology
- Digestive Physiology
Background:
- The exocrine pancreas produces vital digestive enzymes for nutrient breakdown and absorption.
- Disruption of pancreatic function can cause malabsorption and diarrhea.
Purpose of the Study:
- To explore pancreatic diseases causing diarrhea.
- To discuss the pathogenesis and treatment of these conditions.
Main Methods:
- Review of conditions affecting pancreatic parenchyma and ductal obstruction.
- Examination of hormone-secreting pancreatic tumors.
Main Results:
- Significant pancreatic tissue loss (>90%) is often necessary for diarrhea.
- Causes include acute pancreatitis, chronic pancreatitis, pancreatic cancer, and rare hormone-secreting tumors.
Conclusions:
- Pancreatic diseases significantly impact digestion and nutrient absorption.
- Understanding the diverse causes of pancreatic diarrhea is crucial for effective management.
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