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Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Optical coherence tomography--current and future applications.

Mehreen Adhi¹, Jay S Duker

¹Department of Ophthalmology, New England Eye Center, Tufts Medical Center, 800 Washington St., Boston, MA 02111, USA.

Current Opinion in Ophthalmology

|February 23, 2013

Summary

This summary is machine-generated.

Spectral-domain optical coherence tomography (SD-OCT) enhances the diagnosis and management of retinal diseases, particularly choroidal imaging. Future OCT innovations promise improved detection of subtle microstructural changes in chorioretinal conditions.

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Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Area of Science:

Ophthalmology
Medical Imaging
Retinal Diseases

Background:

Optical coherence tomography (OCT) is a noninvasive imaging technique.
OCT provides high-resolution, cross-sectional images of the retina, retinal nerve fiber layer, and optic nerve head.

Purpose of the Study:

Review the current applications of spectral-domain OCT (SD-OCT) in diagnosing and managing retinal diseases.
Emphasize the role of SD-OCT in choroidal imaging.
Discuss future directions and potential clinical uses of OCT technology.

Main Methods:

Analysis of choroidal thickness in healthy and diseased eyes using SD-OCT.
Software improvements enabling detailed analysis.
Review of current literature on SD-OCT applications.

Main Results:

SD-OCT successfully analyzes choroidal thickness in various retinal diseases, including age-related macular degeneration, central serous chorioretinopathy, diabetic retinopathy, and inherited retinal dystrophies.
Future OCT innovations like swept-source technology, Doppler OCT, and en-face imaging may enhance detection of subtle chorioretinal changes.

Conclusions:

Advances in OCT technology improve understanding of pathogenesis, monitoring of disease progression, and quantification of treatment response in posterior segment eye diseases.
Continued hardware and software advancements will further enhance clinical assessment and management of chorioretinal diseases.