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Correlation between differential renal function estimation using CT-based functional renal parenchymal volume and
Debanga Sarma1, Sasanka K Barua, T P Rajeev
1Department of Urology, Gauhati Medical College and Hospital, Bhangagharh, Assam, India.
Summary
Helical CT-based renal parenchymal volume measurement strongly correlates with nuclear renal scans for assessing differential renal function. This suggests CT can serve as a single imaging modality for both anatomical and functional evaluation of impaired kidneys.
Area of Science:
- Radiology
- Medical Imaging
- Nephrology
Background:
- Nuclear renal scan is the standard for differential renal function.
- Helical CT offers potential for combined anatomical and functional kidney assessment.
- Percent renal volume is proposed as a surrogate for differential renal function.
Purpose of the Study:
- To correlate CT-derived renal parenchymal volume with nuclear scan-based differential renal function.
- To evaluate helical CT as a single modality for assessing impaired renal units.
Main Methods:
- Prospective study of 21 patients with unilateral obstructive uropathy.
- Comparison of (99m)Tc - DTPA renal scan with 64-slice helical CT.
- CT-based renal volume calculation and correlation with nuclear scan function using Pearson coefficient.
Main Results:
- A strong positive correlation was found between percent renal volume and percent renal function.
- Correlation coefficients were r = 0.828 (P < 0.001) for obstructed units and r = 0.827 (P < 0.001) for nonobstructed units.
Conclusions:
- CT-based percent renal volume strongly correlates with (99m)TC - DTPA renal scan findings.
- Helical CT can serve as a single radiological test for functional and anatomical assessment of impaired kidneys.
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