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Increased 5-bromo-2’-deoxyuridine incorporation in various brain structures following passive avoidance training in
O I Ivashkina1, M A Zots, D V Bezriadnov
1Laboratory of Neurobiology of Memory, P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia. oivashkina@gmail.com
Abstract:
We studied the effects of training on DNA synthesis intensity in mouse brain. Brain cells where DNA synthesis-associated processes took place under the influence of training were detected by immunohistochemical labeling of DNA molecules with synthetic thymine analogue 5-bromo-2’-deoxyuridine. The number of 5-bromo-2’-deoxyuridine-positive cell increased in various structures of the brain under the influence of training.
